Calcium Antagonists and the Kidney.

The role of calcium antagonists in chronic kidney disease.

PURPOSE OF REVIEW To review goals of antihypertensive treatment in chronic kidney disease in the context of what role calcium antagonists play toward reducing progression of kidney disease. RECENT FINDINGS All recently published guidelines recommend a blood pressure goal of less than 130/80 mmHg in patients with chronic kidney disease. Use of calcium antagonists is not recommended as part of ...

Atherosclerosis, calcium, and calcium antagonists.

Calcium antagonists: Do they equally protect against kidney injury?

Calcium antagonists are a heterogeneous group of drugs that affect not only different channels but different parts of the same channel. These differences translate into different renal hemodynamic effects. This Commentary discusses the implications of these differences for surrogate markers of outcome.

Clinical pharmacology of calcium antagonists. Satellite symposium on calcium antagonists.

A new class of agents has been made available for the treatment of hypertension. These calcium antagonists have rapid bioavailability and dramatic antihypertensive effects through reduction of total peripheral resistance and the vascular resistance of the major target organs of the body. These changes are usually associated with unchanged cardiac output, preserved organ blood flows, maintained ...

Calcium antagonists and endothelial function